Association of glutathione S-transferase M1 polymorphisms in the colorectal cancer risk: A meta-analysis
نویسندگان
چکیده
منابع مشابه
Association of the Glutathione S-Transferase M1, T1 Polymorphisms with Cancer: Evidence from a Meta-Analysis
BACKGROUND Glutathione S-transferases (GSTs) are a family of multifunctional enzymes that are involved in the metabolism of many xenobiotics, including a wide range of environmental carcinogens. While the null genotypes in GSTM1 and GSTT1 have been implicated in tumorigenesis, it remains inconsistent and inconclusive. Herein, we aimed to assess the possible associations of the GSTM1 and GSTT1 n...
متن کاملAssociation of glutathione S-transferase T1, M1, and P1 polymorphisms in the breast cancer risk: a meta-analysis
BACKGROUND Several case-control studies investigating the relationship between genetic polymorphisms of glutathione S-transferase (GST) M1, GSTT1, and GSTP1 (rs1695) and the risk of breast cancer have reported contradictory results. We therefore performed a meta-analysis to clarify this issue. MATERIALS AND METHODS An updated meta-analysis using PubMed and Web of Knowledge databases for the e...
متن کاملGlutathione S-transferase M1 and T1 polymorphisms and cervical cancer risk: a meta-analysis.
There were some studies on the associations between Glutathione S-transferase M1 (GSTM1) and Glutathione S-transferase T1 (GSTT1) polymorphisms and cervical cancer (CC) risk, but the results were inconsistent. Thus, a meta-analysis was performed. The electronic databases PubMed, Science Direct, CBM, and CNKI were searched for possible studies. Finally, 16 studies (1,627 cases and 2,161 controls...
متن کاملAssociation of glutathione S-transferase M1 and T1 polymorphisms and temperament
Mizaj (Temperament) is one of the basic concepts of Iranian Traditional Medicine (ITM), which has great importance in diagnosis and treatment of diseases, as well as maintaining the ideal healthy state of an individual. However, very little is known about the biological mechanisms of mizaj dependence treatment in practical ITM. This study was aimed to evaluate any association between the mizaj ...
متن کاملAssociation between Glutathione S-Transferase T1, M1, and P1 Genotypes and the Risk of Colorectal Cancer
Glutathione S-transferases (GSTs) are enzymes which play an important role in the neutralization of toxic compounds and eradication of electrophilic carcinogens. Genetic polymorphisms within the genes encoding for GSTs may therefore cause variations in their enzyme activity, which may in turn influence the interindividual susceptibility to cancers. In this study, we aimed to investigate the ass...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cancer Research and Therapeutics
سال: 2018
ISSN: 0973-1482
DOI: 10.4103/jcrt.jcrt_446_16